|
KMID : 1201420100030020027
|
|
Journal of Neurocritical Care
2010 Volume.3 No. 2 p.27 ~ p.37
|
|
|
Clinical Approach to the Patients with Delirium in the Neurocritical Care
|
|
Ku Bon-D.
Hong Jong-Hee
|
|
|
Abstract
|
|
|
|
Delirium is a common life-threatening and potentially preventable clinical syndrome. It occurs in up to 70% of patients having neurocritical care. The cause of delirium is multifactorial. Delirium and dementia are highly interrelated and dementia is the leading risk factor for delirium. Specific brain areas especially prefrontal cortex and neurotransmitters especially acetylcholine play an important role in the development of the delirium. Underlying diseases such as stroke, head trauma or dementia make patients more vulnerable to the delirium. Nonpharmacologic therapy should be instituted, including a calm, comfortable environment with the use of orienting influences. Pharmacologic management should be considered for patients whose symptoms would threaten their own safety or the safety of other persons. Therapeutic drug options include atypical neuroleptics or antidepressants. In this review, we discuss the clinical approach and pathophysiology of the delirium focus on the neurocritical management.
|
|
|
KEYWORD
|
|
|
Delirium, Neurocritical care, Clinical approach
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
 
|